Department of Anthropology Faculty

The master’s degree Biological Anthropology is intended to provide holders of degrees in experimental sciences and the humanities with up-to-date training in human biodiversity, its origin, evolution and the biomedical implications. The program responds to the growing demand for specialists in the area of human biology and physical anthropology, contributing knowledge and methodologies pertaining to this area of specialization and related areas e. The program focuses primarily on research and offers students the opportunity both to collaborate with businesses working in this field and to complete their final project in collaboration with outside institutions. These studies are aimed at people who are interested in the following areas: Forensic anthropology and the osteological and molecular techniques used in individual identification. Anthropology applied to archaeology, including taphonomy, demographics and the reconstruction of ancient populations. Human evolution, primatology and prehistory. Molecular anthropology. Biomedical applications of human molecular diversity in cytogenetics, complex diseases and genetic epidemiology.

.Anthropology Subject Guide: Recommended Databases

We address questions concerning human and microbial population history, the evolution of disease-associated genetic variation, and the relationship between cultural, environmental, and genetic variation. In particular, we are interested in how the relationship between humans and microbes has changed through time and how our microbiomes influence health and disease in diverse populations both today and in the past.

JavaScript is disabled for your browser. Some features of this site may not work without it. Though chickens Gallus gallus domesticus are globally ubiquitous today, the timing, location, and manner of their domestication is contentious. Until recently, archaeologists placed the origin of the domestic chicken in

While excavating at Jericho (which dates back to 10, BCE), she discovered city Molecular anthropology is a field changing quickly as new techniques and​.

Slideshows Videos Audio. Here of some of the well-tested methods of dating used in the study of early humans: Potassium-argon dating , Argon-argon dating , Carbon or Radiocarbon , and Uranium series. All of these methods measure the amount of radioactive decay of chemical elements; the decay occurs in a consistent manner, like a clock, over long periods of time. Thermo-luminescence , Optically stimulated luminescence , and Electron spin resonance.

All of these methods measure the amount of electrons that get absorbed and trapped inside a rock or tooth over time. Since animal species change over time, the fauna can be arranged from younger to older. At some sites, animal fossils can be dated precisely by one of these other methods. For sites that cannot be readily dated, the animal species found there can be compared to well-dated species from other sites. In this way, sites that do not have radioactive or other materials for dating can be given a reliable age estimate.

Molecular clock. This method compares the amount of genetic difference between living organisms and computes an age based on well-tested rates of genetic mutation over time.

Carbon-14 dating

Carbon dating , also called radiocarbon dating , method of age determination that depends upon the decay to nitrogen of radiocarbon carbon Radiocarbon present in molecules of atmospheric carbon dioxide enters the biological carbon cycle : it is absorbed from the air by green plants and then passed on to animals through the food chain. Radiocarbon decays slowly in a living organism, and the amount lost is continually replenished as long as the organism takes in air or food.

Once the organism dies, however, it ceases to absorb carbon, so that the amount of the radiocarbon in its tissues steadily decreases. Because carbon decays at this constant rate, an estimate of the date at which an organism died can be made by measuring the amount of its residual radiocarbon.

Dates matter, and inaccurate dating limits how we interpret and understand human history. The discovery of the molecular clock, and the role that molecular.

It doesn’t tick, it doesn’t have hands, and it doesn’t tell you what time of day it is. But a molecular clock does tell time—on an epoch scale. The molecular clock, explains Blair Hedges, is a tool used to calculate the timing of evolutionary events. Instead of measuring seconds, minutes and hours, says Hedges, Penn State professor of biology, the molecular clock measures the number of changes, or mutations, which accumulate in the gene sequences of different species over time.

Evolutionary biologists can use this information to deduce how species evolve, and to fix the date when two species diverged on the evolutionary timeline. The concept of a molecular clock was first put forward in by chemist Linus Pauling and biologist Emile Zuckerkandl, and is based on the observation that genetic mutations, although random, occur at a relatively constant rate. Thus, the theory goes, the number of differences between any two gene sequences increases over time.

As Hedges explains, this thinking led to the idea that the number of mutations in a given stretch of DNA could be used as a measure of time. But before any clock can work, it has to be calibrated, he adds. Setting a molecular clock “begins with a known, like the fossil record,” for a specific species. Then, once the rate of mutation is determined, calculating the time of divergence of that species becomes relatively easy. Broadly speaking, the evolution of important genes occurs more slowly than that of genes with less vital functions.

Molecular anthropology

Hamersly Library LibGuides. Librarians’ Top Picks Anthropology Plus Provides citations for articles and essays on anthropology and archaeology in English and other European languages. PrimateLit Indexes scientific literature on nonhuman primates prosimians, monkeys and apes. The database covers all publication categories articles, books, abstracts, technical reports, dissertations, book chapters, etc.

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Current and Emerging Trends in Human Identification and Molecular Anthropology can be applied to criminal, legal and anthropological investigations.

Anthropology is the study of the origin and development of the human species. Molecular anthropology uses the tools and techniques of molecular genetics to answer anthropological questions, especially those concerning the origins and spread of humans across the globe. These questions mainly fall under the heading of physical or biological anthropology, as opposed to cultural anthropology, which studies social relationships, rituals, and other aspects of culture.

Molecular anthropology attempts to answer such questions as whether humans are more genetically similar to chimpanzees than to gorillas; in what region or regions modern humans first developed; what the patterns are of migration and mixture of early human populations; and whether Neandertals were a different species, and whether they died out or mixed in with modern humans.

Molecular anthropology is perhaps best known for the studies that surround the discovery of “mitochondrial Eve” discussed below , although the meaning of that discovery is often misunderstood. Two major approaches are used in addressing these questions, both of which involve analyzing DNA. The first and most common approach is to compare the DNA of groups of living organisms, for example, comparing humans to humans or humans to primates.

In both cases, the number of differences between the DNA sequences of the two groups are determined, and these are used to draw conclusions about the relatedness of the two groups, or the time since they diverged from a common ancestor, or both. The results of molecular anthropological studies are rarely used alone. Instead, the data are combined with information from fossils, archaeological excavations, linguistics, and other sources.

Sometimes the data from these different sources conflict, however, and much of the controversy in anthropology centers around how much weight to give each when this occurs. The essential postulate on which molecular anthropology is based is that closer genetic similarity indicates a more recent common ancestry.

Workshop on Molecular Evolution

DOI: The source of tuberculosis in ancient Peru, insidious ways that racism can take a toll on health, and the reproductive success of Tibetan highlanders are just a few of the topics that came up recently at the annual meeting of the American Association of Physical Anthropology. One session, sponsored by the American Association of Anthropological Genetics, presented studies of complex phenotypes—that is, traits arising from multiple genetic, environmental, and cultural risk factors.

An adaptation in the hemoglobin concentration of Tibetan mountain dwellers enables them to live and raise families at high altitudes. For example, Cynthia Beall, of Case Western Reserve University, explores how natural selection may be affecting the reproductive success of people who live on the high mountain plateau bordering Tibet and Nepal, about three kilometers above sea level.

The Molecular Anthropology Lab focuses on a multidisciplinary study of human up-to-date experimental methodologies for characterizing uniparental genetic.

The aim of the study is to prepare students for scientific research work at the level corresponding to the current requirements of science. In the new study, concept integrates physical anthropology, including genetics, ecology, and ethology, the sociocultural anthropology in a holistic approach to the study of humans and populations. The task of teaching, in general, is to learn the theoretical foundations of the field and mastering the techniques and methodology of scientific research work.

In physical anthropology, the methods include somatometry, osteometry, anthropological somatotopy, dermatoglyphic, basics of rent genometry and other morphological and morphometric approaches, including the newly introduced 3D distance learning techniques. Study program in anthropology is provided mainly in the field of forensic anthropology and palaeopathology. Molecular genetic studies in addition to forensic applications include analysis receptor genes and genetic polymorphisms in the variable regions of human chromosomes and genetics of musculoskeletal and ecogenetics.

They are also directed at exploring the molecular basis of certain pathological conditions. Especially in the fields of teratology, physiology, neuroscience, and toxicology. From the medical field of study comprises a contact issue of Epidemiology, orthopedics, rehabilitation, endocrinology, pediatrics, and other disciplines. Entrance exams take the form of an interview on the topic of the Ph. Thesis, demonstrating the technical skills of the applicant for a doctoral study program and the ability to work with specialized foreign literature.

The project is assessed by the expert committee.

Molecular Anthropology Laboratory

Biological Anthropology Program Summer Deadlines. For the July 20, target date, proposals will be reviewed in the Fall cycle if received by August 31, Important Message. Please be advised that, depending on the specified due date, the guidelines contained in NSF may apply to proposals submitted in response to this funding opportunity. The Biological Anthropology Program supports multifaceted research to advance scientific knowledge of human biology and ecology, including understanding of our evolutionary history and mechanisms that have shaped human and nonhuman primate biological diversity.

Dr. Elizabeth (Lisa) Matisoo-SmithProfessor of Biological Anthropology and ChairDepartment of Anatomy, University of OtagoThe Powers and Pitfalls of Molecular Archaeology. Date & Time. April 9, – pm to pm. Save to your.

This review broadly summarizes how molecular biology has contributed to our understanding of human evolution. Molecular anthropology began in the s with immunological comparisons indicating that African apes and humans were closely related and, indeed, shared a common ancestor as recently as 5 million years ago.

Although initially dismissed, this finding has proven robust and numerous lines of molecular evidence now firmly place the human-ape divergence at 4—8 Ma. Resolving the trichotomy among humans, chimpanzees and gorillas took a few more decades. Despite the readily apparent physical similarities shared by African apes to the exclusion of modern humans body hair, knuckle-walking, thin tooth enamel , the molecular support for a human—chimpanzee clade is now overwhelming.

More recently, whole genome sequencing and gene mapping have shifted the focus of molecular anthropology from phylogenetic analyses to phenotypic reconstruction and functional genomics. We are starting to identify the genetic basis of the morphological, physiological and behavioural traits that distinguish modern humans from apes and apes from other primates. Most notably, recent comparative genomic analyses strongly indicate that the marked differences between modern humans and chimpanzees are likely due more to changes in gene regulation than to modifications of the genes themselves, an idea first proposed over 30 years ago.

Almost weekly, press releases describe newly identified genes and regulatory elements that seem to have undergone strong positive selection along the human lineage. Loci involved in speech e. FOXP2 , brain development e. ASPM , and skull musculature e. MYH16 have been of particular interest, but some surprising candidate loci e. Exciting new research avenues, such as the Neanderthal Genome Project, promise that molecular analyses will continue to provide novel insights about our evolution.

An Introduction to Molecular Anthropology

The map above depicts the distribution of admixed language pairs in the sample source: B Bickel. Theories on diffusion or borrowability probabilities tend to be based on case studies of language contact where much of linguistic and social history is known or reconstructable [1] [2] [3]. This incurs either a bias towards shallow time depths, or a strong reliance on individual reconstructions of hand- picked features, with little quantification of uncertainty.

Here we examine contact events known from molecular anthropology and estimate diffusion probabilities by sampling features in large-scale typological databases across all domains of linguistic structure [4] [5] [6] [7]. Molecular anthropology has traced physical contact admixture events in the past few thousand years, across several areas in the world. These events are a sufficient though not a necessary condition for language contact.

Historically, molecular anthropology, a term introduced by Emile Zuckerkandl in genes; it is possible to estimate dates of divergence for groups without a.

Looks like you are currently in Russia but have requested a page in the United States site. Would you like to change to the United States site? Mark Stoneking. Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation.

Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics — what genes are, what they do, and how they do it — as well as how genes behave in populations and how evolution influences them.

Probing Question: What is a molecular clock?

Sure, the UIndy Department of Anthropology faculty have years of teaching experience. But more importantly, they have years of actual anthropological and archaeological work experience. Faculty are often called upon to lend their expertise in fieldwork, and their research has been published worldwide.

How do scientists figure out when evolutionary events – like species splitting away from a common ancestor – happened? It turns out our DNA.

The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more life forms diverged. The biomolecular data used for such calculations are usually nucleotide sequences for DNA , RNA , or amino acid sequences for proteins. The benchmarks for determining the mutation rate are often fossil or archaeological dates.

The molecular clock was first tested in on the hemoglobin protein variants of various animals, and is commonly used in molecular evolution to estimate times of speciation or radiation. It is sometimes called a gene clock or an evolutionary clock. The genetic equidistance phenomenon was first noted in by Emanuel Margoliash , who wrote: “It appears that the number of residue differences between cytochrome c of any two species is mostly conditioned by the time elapsed since the lines of evolution leading to these two species originally diverged.

If this is correct, the cytochrome c of all mammals should be equally different from the cytochrome c of all birds. Since fish diverges from the main stem of vertebrate evolution earlier than either birds or mammals, the cytochrome c of both mammals and birds should be equally different from the cytochrome c of fish.

Similarly, all vertebrate cytochrome c should be equally different from the yeast protein. Together with the work of Emile Zuckerkandl and Linus Pauling, the genetic equidistance result directly led to the formal postulation of the molecular clock hypothesis in the early s.

Studying Human Evolution from Ancient DNA

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